Here is the list of 88 drugs marketed in France deemed “dangerous”


Here is the list of 88 drugs marketed in France deemed “dangerous”
Written by madishthestylebar

The specialized journal “Prescrire” made public, this Wednesday, December 7, its 2023 report of drugs to be ruled out. A total of 107 substances appear on this list, 88 of which are marketed in France.

The magazine Prescrire published, this Wednesday, December 7, the list of drugs to be ruled out “for better care”. 107 drugs are thus singled out, including 88 marketed in France.


The list of drugs that Prescrire advises to discard from treatment and replace with better options evolves each year, taking into account the progress of knowledge.

To read on ➡

— Prescribe (@RevuePrescrire) November 29, 2022

All have a marketing authorization, French or European, and “Prescrire” has subjected them to a rigorous evaluation based on documentary research, relevant efficacy criteria for patients and consideration of adverse effects.

Drugs that are more dangerous than helpful

The 107 drugs reported by the specialized journal thus present “an unfavorable benefit-risk balance in all the clinical situations in which they are authorized”.

Concretely, these drugs are considered to be more dangerous than helpful. Sometimes it may just be a specific form or dosage. The specialized journal, the majority of whose articles are written by health professionals, explains, on a case-by-case basis, the reason for the unfavorable benefit-risk balances. Alternatives that are more beneficial to patients are offered where possible.

Read also :
The shortage of drugs is intensifying in pharmacies: here is the list of products concerned

The 88 drugs marketed in France “to be ruled out”

Drugs used in hematology and for transplants
Defibrotide (Defitelio)

Antitumor drugs
Panobinostat (Farydak)
Trabectedin (Yondelis or other)
Vandetanib (Caprelsa)
Vinflunine (Javlor)

Medicines prescribed in cardiology
Bezafibrate (Befizal)
Ciprofibrate (Lipanor or other)
Fenofibrate (Lipanthyl or other)
Dronedarone (Multaq)
Ivabradine (Procoralan or other)
Nicorandil (Ikorel or other)
Olmesartan (Alteis, Olmetec, Alteisduo, Coolmetec, Axeler, Sevikar)
Trimetazidine (Vastarel or other)

Drugs used in dermatology and against allergies
Finasteride 1 mg (Propecia or other)

Mequitazine (Primalan)
Dermal tacrolimus (Protopic or other)
Promethazine Injection (Phenergan)

Diabetes medications
Gliptins: alogliptin (Vipidia, Vipdomet), linagliptin (Trajenta, Jentadueto), saxagliptin (Onglyza, Komboglyze), sitagliptin (Januvia, Xelevia, Janumet, Velmetia) and vildagliptin (Galvus, Eucreas)

Drugs used for weight loss
Orlistat (Xenical or other)

Certain nonsteroidal anti-inflammatory drugs
Aceclofenac (Cartrex or other)
Oral diclofenac (Voltaren or other)
Coxibs: celecoxib (Celebrex or other), etoricoxib (Arcoxia or other) and parecoxib (Dynastat)
Ketoprofen gel (Ketum gel or other)
Meloxicam (Mobic or other)
Piroxicam (Feldene or other)
Systemic tenoxicam (Tilcotil)

Medicines for osteoarthritis
Diacerein (Art 50 or other)
Glucosamine (Flexea or other)

Muscle relaxants
Methocarbamol (Lumirelax)
Thiocolchicoside (Miorel or other)

Medicines for osteoporosis
Denosumab 60 mg (Prolia)

Drugs used in rheumatology
Capsaicin patches (Qutenza)
The combination colchicine, opium powder and tiemonium (Colchimax)
Quinine (Hexaquine, Okimus)

Drugs used in gastroenterology

Obeticholic acid (Ocaliva)
Medicated clays: diosmectite (Smecta or other), hydrotalcite (Rennieliquo), beidellitic montmorillonite or monmectite (Beldelix, Gelox) and kaolin (Gastropax, Neutroses)
Domperidone (Motilium or other)
Droperidol (Droleptan or other)
Metopimazine (Vogalene, Vogalib)
Prucalopride (Resolor)
Tincture of Opium (Dropizal)
Glyceryl trinitrate, 0.4% ointment (Rectogesic)

Drugs used in gynecology and endocrinology
Tibolone (Livial or other)

Medicines against infections
Moxifloxacin (Izilox or other)

Drugs for Alzheimer’s disease
Donepezil (Aricept or other)
Galantamine (Reminyl or other)
Rivastigmine (Exelon or other)
Memantine (Ebixa or other)

Medicines for multiple sclerosis
Natalizumab (Tysabri)

Other drugs used in neurology
Fenfluramine (Fintepla)
Flunarizine (Sibelium)
Oxetorone (Nocertone)
Ginkgo biloba (Tanakan or other)
Naftidrofuryl (Naftilux or other)
Piracetam (Nootropyl or other)
Tolcapone (Tasmar)

cough medicine
Ambroxol (Muxol or other)
Bromhexine (Bisolvon)
Oxomemazine (Toplexil or other)
Pentoxyverine (Pentoxyverine Clarix 0.15%)

Medicines for sore throats
Alpha-amylase (Maxilase or other)
Tixocortol Oral Spray (Rhinadvil Sore Throat)
Medications used in pneumology and ENT
Oral and/or nasal decongestants: ephedrine, naphazoline, oxymetazoline, phenylephrine, pseudoephredine, tuaminoheptane
Nintedanib (Ofev)

Medicines for depression
Agomelatine (Valdoxan or other)
Citalopram (Seropram)
Escitalopram (Seroplex or other)
Duloxetine (Cymbalta or other)
Milnacipran (Milnacipran Arrow or other)
Venlafaxine (Effexor LP or other)
Esketamine nasal spray solution (Spravato)
Tianeptine (Stablon or other)

Other psychotropics
Dapoxetine (Priligy)
Etifoxine (Stresam)

Drugs for smoking cessation
Buproprione (Zyban)

Drugs used in urology
Oral pentosan polysulfate (Elmiron)

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